CEFPOWER

Generic Name
Cefpodoxime
Therapeutic Category
Respiratory
Dosage Form
Suspensions
Strength
100mg, 200mg, 40mg/5ml, 100mg/5ml
Pack Size
1 x 10, 90ml
Registration Number
45294 | 45293 | 47178 | 45295

Product Description

Cefpodoxime proxetil is indicated for the trea tment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions listed below :

  • Acute otitis media caused by Streptococcus pneumoniae (excluding penicillin-resistant strains), Streptococcus pyogenes, Haemophil us influenzae (including beta-lactamase-producing strains), or Moraxella (Branhamella) catarrhalis (including beta-lactamase-producing strains) .

  • Pharyngitis and/or tonsillitis caused by Streptococcus pyogenes . 

  • Community-acquired pneumonia caused by S. pneumoniae or H. influenzae (including beta-lactamase-producing strains) . 

  • Acute bacterial exacerbation of chronic bronchitis caused by S. pneumoniae, H. influenzae (non-beta-lactamase-producing strains only), or M. ca tarrhalis . Data are insufficient at this time to establish efficacy in patients with acute bacterial exacerbations of chronic bronchitis caused by beta-lactamase-producing strains of H. influenzae .

  • Acute, unco mplicated urethral and cervical gonorrhea caused by Ne isseria gonorrhoeae (including penicillinase-producing strains) .

  • Acute, uncomplicated anorectal infections in women due to Neisseria gonorrhoeae (including penicillinase-producing strains) . 

  • Uncomplicated skin and skin structure infections caused by Staphylococcus aureus (including penicillinase-producing strains) or Streptococ cus pyogenes . Abscesses should be surgically drained as clinically indicated .

  • Acute maxillary sinusitis caused by Haemophilus influenzae (including beta-lactamase-producing strains), Streptococcus pneumoniae, and M oraxella catarrhalis .

  • Uncomplicated urinary tract infections (cystitis) caused by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, or Staphylococcus saprophyticus .

Indication

Cefpodoxime proxetil is an orally administered, extended spectrum, semi-synthetic antibiotic of the cephalosporin class . The chemical name is (RS)-1(isopropoxycarbonyloxy) ethyl(+)-(6R,7R)-7-[2-(2-amino-4-thiazolyl)-2-{(Z)methoxyimino}acetamido]-3-methoxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate . Its empirical formula is C21H27N5O9S2 . The molecular weight of cefpodoxime proxetil is 557.6 .

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